{"id":87303,"topic":"peptides","source":"The Manila Times","title":"European Commission approval of ICOTYDE™▼(icotrokinra) ushers in new era for first-line systemic treatment of plaque psoriasis with a targeted oral peptide - The Manila Times","url":"https://www.manilatimes.net/2026/09/21/tmt-newswire/globenewswire/european-commission-approval-of-icotydeicotrokinra-ushers-in-new-era-for-first-line-systemic-treatment-of-plaque-psoriasis-with-a-targeted-oral-peptide/2429640","url_hash":"fa7a4cf9a8f9b126f6fd3d4a76718054a83cd376","author":"","summary":"<a href=\"https://news.google.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?oc=5\" target=\"_blank\">European Commission approval of ICOTYDE™▼(icotrokinra) ushers in new era for first-line systemic treatment of plaque psoriasis with a targeted oral peptide</a>&nbsp;&nbsp;<font color=\"#6f6f6f\">The Manila Times</font>","content":null,"image_url":null,"lang":"en","published_at":"2026-09-21T14:51:50+00:00","fetched_at":"2026-09-21T15:15:10+00:00","status":"read","starred":0,"extract_state":"failed","summary_auto":null,"cluster_id":null,"extract_retries":2,"extract_error":"http_403","contract_version":"news_item.v1","format_contract_version":"news_item_formats.v1","dedup_url":"https://www.manilatimes.net/2026/09/21/tmt-newswire/globenewswire/european-commission-approval-of-icotydeicotrokinra-ushers-in-new-era-for-first-line-systemic-treatment-of-plaque-psoriasis-with-a-targeted-oral-peptide/2429640","quality_profile":{"profile_version":"extraction_quality.v2","bucket":"failed","confidence":0.0,"failure_kind":"http","retryable":false,"retry_after_attempts":0,"reason":"Low confidence: HTTP extraction failure (http_403).","operator_guidance":{"severity":"action_required","recommended_action":"manual_review","next_step":"Open diagnostics and review the original source manually before use.","operator_label":"Manual review","can_retry":false,"can_use_summary":false,"diagnostics_required":true},"content_depth":{"contract_version":"content_depth.v1","category":"summary_only","label":"Summary only","has_full_text":false,"has_summary":true,"content_length":0,"summary_length":1180,"usable_text_length":1180,"source_field":"summary"},"legacy_collapsed":false,"signals":{"extract_state":"failed","extract_error":"http_403","extract_retries":2,"content_length":0,"summary_length":1180}},"news_item":{"id":87303,"canonical_url":"https://www.manilatimes.net/2026/09/21/tmt-newswire/globenewswire/european-commission-approval-of-icotydeicotrokinra-ushers-in-new-era-for-first-line-systemic-treatment-of-plaque-psoriasis-with-a-targeted-oral-peptide/2429640","source_url":"https://www.manilatimes.net/2026/09/21/tmt-newswire/globenewswire/european-commission-approval-of-icotydeicotrokinra-ushers-in-new-era-for-first-line-systemic-treatment-of-plaque-psoriasis-with-a-targeted-oral-peptide/2429640","title":"European Commission approval of ICOTYDE™▼(icotrokinra) ushers in new era for first-line systemic treatment of plaque psoriasis with a targeted oral peptide - 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